Synonyms: CORYNINE HYDROCHLORIDE;APHRODINE HYDROCHLORIDE;APHROSOL HYDROCHLORIDE;17-HYDROXYYOHIMBAN-16-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE;17A-HYDROXYYOHIMBAN-16A-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE;YOHIMBE HCL;YOHIMBINE HCL;YOHIMBINE HYDROCHLORIDE
CAS No.: 65-19-0
Packaging: 1kg/Aluminum foil bag
Molecular Formula: C21H26N2O3.HCL
Appearance: Fine powder white to cream
Chemical Properties white to slightly yellow powder
Usage Indole alkaloid with α2-adrenergic blocking activity. Mydriatic. Used in the treatment of neurological disorders.
Usage alpha adrenergic blocker, mydriatic, antidepressant
Usage vasodilator, neuromodulator
Usage a2-adrenergic antagonist, used for erectile dysfunction
Yohimbine common brand names are: Erex, Testomar, Yocon, Yohimar, Yohimbe. It is a stimulant with aphrodisiac and mild MAOI effects that primarily acts as an antagonist of α2 receptors. It is sometimes sold as prescription medicine in pure form for the treatment of xerostomia and sexual dysfunction. Yohimbine was explored as a remedy for type 2 diabetes in animal and human models carrying polymorphisms of the α2A-adrenergic receptor gene.
Yohimbine hydrochloride Applications:
1). Sexual dysfunction--------The NIH states that yohimbine hydrochloride is the standardized form of yohimbine that is available as a prescription medicine in the United States, and that it has been shown in human studies to be effective in the treatment of male erectile dysfunction. Yohimbine has been shown to be effective in the treatment of orgasmic dysfunction in men. Yohimbine has also been used to treat hypoactive sexual desire disorder (under active libido) in women.
2). Fat loss--------Yohimbine has shown to increase lipolysis in multiple studies.Administered prior to exercise, it boosts lipolysis and serum FFA levels both during and following exercise; blockade of adipocyte alpha-2 adrenoreceptors makes at least a modest contribution to this pro-lipolytic activity. Pre-exercise yohimbine administration has the potential to down-regulate the lipoprotein lipase activity of visceral adipocytes, increase lipolysis in refractory gynoid fat depots, and improve the impaired lipolytic response to exercise in the elderly
|Appearance||White fine powder||Complies|
|Assay (HPLC) On dry basis||Yohimbine HCL≥98.0%||99. 3%|
|Sieve analysis||NLT 100% pass 80 mesh||Complies|
|Boiling point||542.979°C at 760 mmHg||Complies|
|Vapour Pressur||0mmHg at 25°C||Complies|
|Specific Rotation||+100º to +105º||+103.80º|
|Solubility||Slightly soluble in Water/Alcohol||Complies|
|Loss on Drying||≤1%||0.7%|
|Residue on Ignition||≤1%||0.87%|
|Microbiology|| || |
|Total Plate Count||<1000cfu/g||Complies|
|Yeast & Moulds||<100cfu/g||Complies|
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