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Wuhan Magic Biotechnology Co., Ltd.

Health Care, Aicar, Acadesine manufacturer / supplier in China, offering Natural Health Care Raw Sarms Powder Acadesine Aicar CAS 2627-69-2, Raw Steroid Norethindrone Acetate CAS No. 51-98-9 for Health Care, GMP Standard Steroid Norethindrone Acetate CAS No. 51-98-9 for Health Care and so on.

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Supplier Homepage Product Sarms Growth Hormone Natural Health Care Raw Sarms Powder Acadesine Aicar CAS 2627-69-2

Natural Health Care Raw Sarms Powder Acadesine Aicar CAS 2627-69-2

FOB Price: US $1-3 / g
Min. Order: 10 g
Min. Order FOB Price
10 g US $1-3/ g
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Port: Hong Kong, Hong Kong
Production Capacity: 500kg/Month
Payment Terms: T/T, Western Union, Paypal, Money Gram, Bitcoin

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Basic Info
  • Model NO.: 2627-69-2
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • M.F.: C9g14n4o5
  • Appearance: White Powder
  • Transport Package: Suitable Package According to Your Quantity
  • Origin: China
  • Powder: Yes
  • Certification: GMP, ISO 9001, BP
  • State: Solid
  • CAS No.: 2627-69-2
  • M.W.: 258.231
  • Trademark: whmoli
  • Specification: 99
  • HS Code: 3001200020
Product Description
Basic Info
Product NameAicar
Other NameAcadesine
Purity98%min by HPLC
CAS No.2627-69-2
M.W.258.231
M.F.C9G14N4O5
Melting Point214-215ºC
AssayHPLC;HNMR;LCMS
AppearanceWhite powder
Applicationmuscle building

Fat Loss
AICAR is a peptide,which is an intermediate within the generation of inosine monophosphate and directly related to metabolic regulation.The most important mechanism that AICAR is known for is its ability to block enzymes both in intracellular and extracellular levels,which,in turn,allows for an accelerated stimulation of glucose uptake and increase protein kinases in skeletal muscle tissue.These two functions allow for more energy conversion,which helps burn fat and also sustain output in activity.This is what scientists and athletes/bodybuilders are interested in.

AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion.With these regulatory enzymes inhibited,the affected cells can in turn boost the amount of glucose that can be received,and it can also increase its level of energy conversion.Additionally,the peptide's presence has been determined to aid in lowering programmed cell death,a process that is also known as apoptosis.

AMP-activated Protein Kinase
Aicar's principal mechanism of action is activation of AMPK (AMP-activated protein kinase.) Activating AMPK,therefore,causes the same cellular machinery (so to speak) to be turned on as if the cell were energy deprived,for example from intensive exercise,or from low caloric intake.

Aicar,at sufficient and quite substantial concentration,is effective at activating AMPK and inducing a cellular state as if exercise had been performed,or energy stores were low and fat therefore needed to be burned.

AICAR uses metabolic pathways to block certain enzymes,which allows for AMP-activated protein kinase.This can be explained to the layperson like this: once you take a substantial amount of aicar,it tricks your body at a cellular level in to thinking that exercise has just been preformed. Since the body thinks it has just done a considerable amount of exercise,the energy cycle at the cellular level starts converting fuel sources,like fatty acids,to output the energy that was thought to have been spent during exercise.This can have a direct effect on the level of endurance activity and the sustainability of that activity.Insulin sensitivity is also noted to be one action that AICAR produces,as the body will think it just went through a series of exercises.Interestingly,in animal studies with obese mice,aicar showed all of the peptides benefits for obese diet induced mice,yet the healthy lean mice did not reap any of the benefits of insulin sensitivity or increase in glucose uptake.That being said, the application in bodybuilding does not seem very suitable, as these mechanisms are targeted for the out-of-shape and over-weight.

Protect against ischemic Injury
Interestingly,aicar has been shown to protect against ischemic injury.This type of injury is directly related to the restriction of blood to tissues,which can cause insufficient amounts of oxygen and glucose needed to keep the tissue alive.This can lead to thrombosis,embolisms,and vasoconstriction.Aicar can be used as a stabilizing peptide for ischemic episodes,and it can allow for proper blood flow to the myocardium (heart).This function is very interesting,as aicar could be fundamentally used to treat the heart muscle in the aftermath of a heart attack.This might reduce the possibility for ischemic injuries.Abnormal growths of heart tissues and heart valve function have also been altered in animal studies that used the peptide aicar,which is a downside.
 
Functions
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha.In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research.Additionally,research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase),and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside,and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC).AICAR is an inhibitor of Hsp90,mTOR and p70 S6 Kinase.

Company profile: 
We are Wuhan Magic Biotechnology Co., Ltd. and our main products include:pharmaceutical intermediates,injectable anabolic steroids,health care products,sarms,antibiotics,cardiovascular drugs,cephalosporin products,bile acid products,weight loss drugs and so on.Which is widely used in bodybuilding,medicine,food&beverage,health care and other industries.We have much experiences in the field for many years.We can give you the products in very competitive price with higher quality.

Our Advantages:
1.Rich experience.We are a professional trading company in China for many years,our products have exported to Germany,Spain,UK,USA,Australia,Middle East and so many other countries,and we have got very good feedback from our customers,we had Established many long friendly relations of cooperation. 

2.Great quality,purity and competitive price.Different country with different and suitable way of packing.Packing pictures will be sent to you as soon as possible after your payment.

3.Safe and fast delivery. 

4.Good after-sales service. 
a).We will ship the goods within 5days after get your payments.If you want to cancel or change order,please tell me within 24hours after you finish the payment.So we both can make the best of the bad bargain.
b).We will ship the goods that you order from us by EMS,HKEMS,DHL,UPS,or FedEx.We will decided to choose which courier depend on Different countries.To find the best way to delivery the goods for you.
c).If the goods were lost or not received for other reasons,please contact me Immediately.

Welcome to inquiry!

If you have any problems or you want to know more informations,please contact us anytime.We will always be at your service!
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